Viral Vectors And Plasmid DNA Manufacturing Market Is Gaining Major Traction With Oxford Biomedica Plc Entering Into A 3-Year Agreement With Boehringer Ingelheim For The Manufacture And Supply Of Various Types Of Viral Vectors
Viral Vectors are proteins that have
been discovered to be essential for the spread of various viruses and
infectious agents. These proteins can cause serious health risks if they are
improperly introduced or if a wrong agent is used to fight them off. Viral
vectors have often been used in various gene therapy procedures with the
ultimate objective of curing various ailments in the biological fields of
neurology, gene therapy, cancer, and metabolic disorder. Clinical studies
regarding viral vectors remain one of the key factors in the manufacturing of
viral vectors. Plasmids are used to deliver DNA contain genes for antibiotic
resistance. In fact, scientists have developed many uses of plasmids and
created software to record the DNA sequences of plasmids for applications in
various techniques. Thus, such continuous R&D activities can potentially
stimulate growth of the viral vectors and plasmid DNA manufacturing market.
Recently, in April 2021, Oxford
Biomedica plc entered into a new three-year Development & Supply Agreement
(DSA) with Boehringer Ingelheim for the manufacture and supply of various types
of viral vectors.
The cases of genetic disorders such
as Down syndrome, Cystic Fibrosis, Huntington’s disease, and hemophilia have
gone up over the years worldwide. As per the Cystic Fibrosis Foundation (CFF),
over 70,000 people across the globe live with cystic fibrosis with around 1,000
new cases diagnosed each year. As per the Centers for Disease Control and
Prevention (CDC), each year around 6,000 babies are born with Down syndrome in
the U.S. Viral vectors are crucial in the diagnosis of these types of genetic
disorders. Thus, such factors can stimulate growth of the viral vectors and
plasmid DNA manufacturing market.
Due to the alarming rate at which
these viruses get resistant to medicines, it is very important to use
appropriate gene therapy procedures for patients who are prone to receiving
infections from these deadly diseases. The most dangerous aspect of these viral
vectors is that a large number of people may get exposed to the virus if the
medical practitioner uses the wrong type of approach in treating patients with
neurological disorders. That being said, one of the major challenges in the
adoption of viral vectors is the high cost of gene therapies. The cost of
production is weighed against the value of a life saved or improved quality of
life of a specific time period. Besides, there are many hurdles related to
viral vector manufacturing capacity that can potentially inhibit growth of the
viral vectors and plasmid DNA manufacturing market.
Gene therapy applications based on
viral vectors are also very helpful in fighting against other
transgene-associated diseases. It is necessary for professionals to be more
careful in applying these applications in order to prevent untoward events such
as side effects. As far as regional impact is concerned, developed countries in
North America such as the U.S. seem to be gaining robust traction in the
regional viral vectors and plasmid DNA manufacturing market. This is typically
due to frequent product approvals from the U.S. Food and Drug Administration
(FDA).
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