High Prevalence of Pulmonary Arterial Hypertension and R&D of New Formulations of Treprostinil to Augment Growth of Treprostinil Drugs Market

Treprostinil Drugs Market

 Treprostinil is an antihypertensive agent used to treat patients with pulmonary arterial hypertension. It can also be used in the treatment of Degos disease, an extremely rare disorder in which small and medium-sized arteries become blocked (occlusive arteriopathy), restricting the flow of blood to affected areas. 

Market Dynamics 

The high prevalence of pulmonary arterial hypertension is expected to propel the growth of the treprostinil drugs market. For instance, according to the study, ‘High Geographic Prevalence of Pulmonary Artery Hypertension: Associations with Ethnicity, Drug Use, and Altitude’, published in February 2020, in the journal Pulmonary Circulation, the overall pulmonary arterial hypertension incidence was 14 cases per million and the annual period prevalence of pulmonary arterial hypertension was 93 cases per million.

R&D of new formulations of treprostinil is expected to offer lucrative growth opportunities for players in the treprostinil drugs market. For instance, in November 2020, the U.S. Food and Drug Administration issued a complete response letter for the New Drug Application of Liquidia Technologies, Inc., a wholly-owned subsidiary of Liquidia Corporation, for LIQ861 (treprostinil) inhalation powder for the treatment of pulmonary arterial hypertension. 

A decline in new prescriptions for treprostinil-based products is expected to hinder the growth of the treprostinil drugs market. For instance, United Therapeutics reported a decline in new prescriptions from the company’s treprostinil-based products during the month of April 2020.

Among regions, North America is expected to witness significant growth in the treprostinil drugs market, owing to R&D of new formulations of treprostinil in the regions. For instance, in September 2020, Alembic Global Holdings SA, a wholly owned subsidiary of Alembic Pharmaceuticals Limited, received tentative approval from the U.S Food & Drug Administration for its Abbreviated New Drug Application Treprostinil Injection, 20 mg/20 ml (1 mg/ml), 50 mg/20 ml (2.5 mg/ml), 100 mg/20 ml (5 mg/ml), and 200 mg/20 ml (1 O mg/ml), Multiple-Dose Vials, for the treatment of pulmonary arterial hypertension.

Competitive Analysis 

Major players operating in the treprostinil drugs market include, United Therapeutics, Novartis AG, Liquidia Technologies, Inc., Alembic Global Holdings SA, and Teva Pharmaceutical Industries Ltd. 

Major players operating in the treprostinil drugs market are focused on approval and launch of new products to expand their product portfolio. For instance, in December 2020, United Therapeutics Corp. received the U.S. Food and Drug Administration’s orphan drug designation for Tyvaso (treprostinil) Inhalation Solution for the treatment of patients with idiopathic pulmonary fibrosis. 

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