Zopiclone, a Nonbenzodiazepine That Increases Normal Transmission of Neurotransmitter Gamma-Aminobutyric Acid

 

Zopiclone

Zopiclone is a prescription sleep aid that can be taken to treat bad bouts of insomnia. High prevalence of insomnia is expected to boost demand for such sleeping aids. According to the study, ‘Prevalence of Sleep Disturbance and Hypnotic Medication Use in Relation to Sociodemographic Factors in the General Japanese Adult Population’ published in 2020, in the Journal of Epidemiology, prevalences of insomnia (INS), difficulty initiating sleep (DIS), difficulty maintaining sleep (DMS), poor perceived quality of sleep (PQS), and hypnotic medication use (HMU) were 17.3%, 8.6%, 12.9%, 17.8%, and 3.5% in males and 21.5%, 12.6%, 16.2%, 20.2% and 5.4% in females.

Zopiclone is a nonbenzodiazepine that increases the normal transmission of the neurotransmitter gamma-aminobutyric acid in the central nervous system. It helps you fall asleep more quickly, and also helps stop you waking up during the night. The sedative is generally available in tablet form. Long term use of this drug is not recommended and is often linked to risk of dependency when this drug is prescribed for substance users with a comorbid psychiatric illness.

Zopiclone has both the potential for becoming an addictive drug and also for being a recreational drug. While many have indicated that the current addictive potential of this and several other drugs is lower than for most other benzodiazepines, care should be taken when prescribing this drug for insomnia.

Zopiclone is sold under the brand name Imovane among others. It was initially approved by the United States Food and Drug Administration as a prescription sleep aid for those who are hyperglycemic, anxious, or have insomnia caused by decreased oxygenation. It is also used to treat depression and chronic pain. Since the FDA has approved Zopiclone to treat insomnia in non-hypnotic patients, it can be purchased over-the-counter with a valid medical prescription.

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